Immune-mediated hemolytic anemia in cats referring to Veterinary Teaching Hospital of Tehran (2006-2007)
نویسندگان: ثبت نشده
چکیده مقاله:
Immune-mediated hemolytic anemia (IMHA) is characterized by the destruction of erythrocytes or sometimes bone marrow erythroid precursors mediated by immunoglobulins (IgG, IgM), with or without complement (C 3). The main objectives of this study were to assess the laboratory test results of IMHA and to investigate its possible underlying causes in cats referring to the Veterinary Teaching Hospital of Tehran. The Coombs’ test (CT) was performed in 74 cats with PCV below 0.35. The test was positive in 26 cats. These positive CT cats were categorized into four groups based on the PCV ranges and type of anemia including: Group A: 9 of 26 cats had nonregenerative anemia (PCV median, 0.22) (1 feline leukemia virus positive which had erythroleukemia, 1 feline infectious peritonitis positive, 1 with Hemoplasma spp., 3 with renal failure, 2 with inflammatory disease and 1 with no diagnosis). Group B: 4 cats (PCV median, 0.31) had a regenerative anemia with severe dehydration. Group C: the other 9 cats with a normal range of PCV (median, 0.34) involved with various conditions (vaccination, parturition, acetaminophen poisoning, osteoporosis, and renal failure). Group D: the remaining 4 cats with a marginal range of PCV (median, 0.30) had a history of inflammatory disease and drug therapy. The results of this study indicated that infectious diseases and drug therapy were the main factors associated with positive Coombs’ test results.
منابع مشابه
Leptospirosis and immune-mediated hemolytic anemia: A lethal association
Immune-mediated hemolytic anemia (IMHA) is a common cause of anemia in dogs. The immune aggression towards erythrocytes can be triggered by many pathological conditions such as infection, inflammatory disease or neoplasia. Upon ruling out any eliciting conditions, a diagnosis of the primary immune-mediated disease can be made. In this particular case of severe anemia (tested positive for circul...
متن کاملImmune-mediated hemolytic anemia.
Hemolytic anemia due to immune function is one of the major causes of acquired hemolytic anemia. In recent years, as more is known about the immune system, these entities have become better understood and their treatment improved. In this section, we will discuss three areas in which this progress has been apparent. In Section I, Dr. Peter Hillmen outlines the recent findings in the pathogenesi...
متن کاملImmune-mediated Hemolytic Anemia
s and Unpublished Data: a. Garcia-Pereira BL, Jutkowitz LA, McBride BL, Brown AJ. Prevalence of portal vein thrombosis and pulmonary thromboembolism in dogs with immune-mediated hemolytic anemia. J Vet Emerg Crit Care 2009;19:A8 (abstract). b. McBride BL, Jutkowitz LA, Garcia-Pereira BL. Association between length of storage of transfused red blood cells (RBCs) and outcome in dogs with immune-m...
متن کاملOccurrence and potential causative factors of immune-mediated hemolytic anemia in cattle and river buffaloes
The main objectives of this study were to determine the occurrence and potential causative factors of Immune-mediated hemolytic anemia (IMHA) in native cattle and water buffaloes from southwest of Iran. Fifty-three anemic animals (37 cattle and 16 buffaloes) were studied. A full clinical history and physical examinations were undertaken for all animals. Four clinically healthy cattle and four h...
متن کاملMultiple splenic infarctions in a dog with immune-mediated hemolytic anemia: therapeutic implications
Background: Splenic infarction (SI) is a rare clinical entity seldom encountered in veterinary medicine. Its most frequent causes include thromboembolic status, splenomegaly, and cardiac disease. Although thrombotic elements from the circulation provide the most common context for thromboembolic SIs, immune-mediated hemolytic anemia (IMHA) has not been reported as an underlying...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ذخیره در منابع من قبلا به منابع من ذحیره شده{@ msg_add @}
عنوان ژورنال
دوره 10 شماره 4
صفحات 373- 377
تاریخ انتشار 2009-12-30
با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.
کلمات کلیدی
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023